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Liu J.-Y
Inactivation of testosterone occurs primarily in the liver

The phenotypic effects of Pnldc1 knockouts are notably less severe than those of Tdrkh knockouts, with milder impairments in piRNA synthesis and germ cell development, even though both Pnldc1 and Tdrkh knockout animals have similar deficits in piRNA 3-end trimming [454, 455]

Some evidence suggests that receptors and G proteins are actually pre-coupled
