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The generation, activation, and polarization of monocyte-derived macrophages in human malignancies

10.1016/j.dld.2014.02.010 138

In the next step, isocitrate dehydrogenase (IDH) metabolizes isocitrate to -ketoglutarate (-KG), which is further metabolized to succinyl-CoA by -KG dehydrogenase complex

Vulpe, C
