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Moreover, there is strong evidence that L-carnitine impacts mitophagy and mitochondrial biogenesis, which are both vital to mitochondrial quality control

Currently, several important guidelines, including International Atherosclerosis Society (IAS) guideline [20], National Lipid Association (NLA) guideline and National Institute for Health and Care Excellence (NICE) guideline [21], have flagged non-HDL-C as a primary therapeutic target for patients with CHD

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Li et al., 2017) reflect differences in the mechanisms involved in METH toxicity on monoaminergic systems between the various routes of METH administration