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Taken together, SCG101 TCR-T mediated a high target-specific anti-tumor activity and initiated T-cell persistence in vivo
The reduced production of ATP is mainly caused by the impaired function of the oxidative phosphorylation system (OXPHOS), which includes a series of redox reactions ending in oxygen, during which the mitochondrial electron transport system (ETS) transfers electrons between the complexes of the respiratory chain with the formation of the proton motive force, but also of superoxide [9]
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