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In addition to renal activation, peripheral tissues such as immune cells also express CYP27B1, indicating that vitamin D can be locally activated to exert paracrine effects (7)
10.1152/ajpgi.00093.2017 74 MerryT
doi: 10.1038/aja.2011.96
doi: 10.1016/j.pnpbp.2008.10.004
