Department of Defense SBIR 2014.3
US$ 27.33
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Description
Phenotypic variability in deficiency of the subunit of succinate-CoA ligase
These peptides may not target lupus directly, but their mechanisms address symptoms or complications common in the disease
Annapurna, A., Vishala, T
Several studies have shown that SDH-deficient cells exhibit increased tumorigenesis and that this increase is reversed by the addition of -KG, supporting the idea that succinate accumulation contributes to tumorigenesis through epigenetic modification 100
