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Our findings further suggest a need to study such pathways with consideration of the interactions with first-line pharmacotherapy, and the potential use of antioxidants as supplemental therapy

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Melphalan-induced DNA damage in vitro as a predictor for clinical outcome in multiple myeloma
6.3.3 Trial-design lessons Future trials should: enrich for participants with high redox/ferroptosis burden (biomarker-enriched enrollment)