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Now, Tfh cells are divided three subsets: Tfh1 (CXCR3 + CCR6 ), Tfh2 (CXCR3 CCR6 ), and Tfh17 (CXCR3 CCR6 + ) cells [91]

4 The patient, who had been placed on daily folic acid (5 mg/day), continued to require an average of 2.5 blood units per year until, at the age of 25, he developed obstructive jaundice due to gallstones

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