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The following fillers are hyaluronic acid fillers which can respond to hyaluronidase: Belotero, Restylane, Restylane Silk, Restylane Lyft (previously Perlane), Juvederm, and Juvederm Voluma

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Then all animals were randomly divided into five groups (n=10) as follows: group I (model control) rats were administrated plain hydrogel alone