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Description
The increased DHA uptake in mutant cells produced oxidative stress, increasing the level of reactive oxygen species (ROS) in cells because intracellular DHA was rapidly reduced back to vitamin C at the expense of glutathione (GSH), a master antioxidant in cells

RGD peptide modification improves its targeting capability

Newton, Julia L (April 2, 2015), "Abnormalities of AMPK activation and glucose uptake in cultured skeletal muscle cells", PLoS One , 10 (4), doi:10.1371/journal.pone.0122982, PMID 25836975 Dobberstein, Linda J

Topical application uses concentrations between 0.005 and 0.1 percent in a cream base, applied twice daily to affected areas
