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Despite their different etiologies, these wounds share several common features (e.g., prolonged or excessive inflammation, persistent infections)
10.3390/jcm9113746 [DOI] [PMC free article] [PubMed] [Google Scholar] 274.Donath MY, Shoelson SE
Notes: Chemically related to neostigmine, but has a longer duration of action and less GI effects Figure 2
Under normal conditions, there is a well-regulated equilibrium in the GI mucosa between inflammatory cytokines (such as TNF-, IL-1, IL-6, IL-8, IL-17, and IL-23) and anti-inflammatory cytokines (like IL-5, IL-10, IL-11, and TGF-) (75)
