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Baicalin and baicalein in modulating tumor microenvironment for cancer treatment: A comprehensive review with future perspectives

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NOXs are a group of seven membrane-bound multi-component enzymes, namely NOX1, NOX2 (gp91phox), NOX3, NOX4, NOX5, DUOX1, and DUOX2, capable of oxidizing NADPH to NADP + , leading to the generation of superoxide by one-electron reduction of oxygen 14
