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Has been opposed several times mainly by nurses
2) the increase in vitamin B 12 level did not interfere with Hcy values, which were similar between groups (11 mol/L vs 9 mol/L) and are within the normal range, 515 mol/L 139

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Genetic polymorphisms in the HNMT gene have been associated with altered histamine sensitivity, and factors that inhibit HNMT (including certain MAO inhibitors and alcohol) can compound histamine accumulation at the cellular level