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, 2015), and contributes to the suppression of cell death responses (Lin et al

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Another study done on humans show that acyl ghrelin inhibits steroid biosynthesis by ovarian granulosa lutein cells [260]

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Similarly, tolvaptan, the only FDA approved drug for autosomal dominant polycystic kidney disease (ADPKD), is difficult to tolerate due to side effects such as nausea and polyuria, and has been found to cause hepatotoxicity in certain patients [14]

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