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Interestingly, research has shown that even in animals lacking beta-3 adrenergic receptors, acute AOD-9604 administration still increased energy expenditure and fat oxidation, suggesting additional metabolic pathways may be involved beyond the primary beta-3 receptor mechanism

But mostly, thats just because it feels better
In summary, various mechanisms do exist to achieve the purpose of NETs formation through specifical stimuli

Mechanisms for mechanical damage in the intervertebral disc annulus fibrosus
