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In animal models, a hydroalcoholic extract of tribulus relieved cisplatin-induced renal toxicity, perhaps via diuretic effects that increase drug excretion, scavenging free radicals via increase in antioxidant enzymes, suppressing inflammatory agents, and acting on organic cation transporter 2 (OCT2) proteins (41)
Mitochondria are the primary sites for the generation of ROS within cells
Cancer Lett 369:2027
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