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10.1126/science.179.4077.1011 [DOI] [PubMed] [Google Scholar] Petaja-Repo U

Others then used a similar model to demonstrate that SF treatment enhanced long-term potentiation in the hippocampus, a critical brain region for memory formation

189 By modulating fat and glucose metabolism in response to energy fluctuations, sirtuins serve as essential regulators of the complex network responsible for maintaining energy balance

These results support the increasingly well-established systems approach, which views ASD as a disorder encompassing interdependent biological networks, ranging from mitochondria to the immune system to the gut-brain axis [129, 130]