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10.1055/s-0030-1265293 147

In a small case-control study published in Antioxidants , researchers found that adults with age-related decline in muscle integrity were more likely to have low blood glutathione levels and an imbalance between oxidants and antioxidants than those with healthier muscle mass

Other genes, although with ARE motifs, present CpG islands in their proximal promoters such as GCLC and GCLM, which are characterized by significant association of active histone codes such as H3K4Me1-3, H3K9Ac, H3K27Ac, and H3K79Me2, suggesting a regulatory role of CpG islands in chromatin modifications

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