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In the latter case, the elevated Hb and Hct levels are caused by a contraction of the plasma volume and not by an increase in the RBC mass, so-called spurious polycythemia (pseudopolycythemia), or Gaisbocks syndrome, and may not warrant therapeutic intervention
This study elucidates the non-selective activation mechanism by determining cryo-EM structures of Cagri bound to AMYR-G and CTR-G complexes
J., Jarzembowski J
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