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In a rat model of focal middle cerebral artery embolism (MCAO), PNS significantly ameliorated focal CIRI by decreasing the volume of cerebral infarction and inhibiting the release of the inflammatory factors IL-1 and TNF- (Sun et al., 2020)

Acetylcholine, phospholipids, autoantibodies, and a word of caution Acetylcholine and antiphospholipid autoantibodies are seen in various autoimmune and chronic illnesses

FIGURE 1 GATases are widely distributed in all kingdoms of life and are used to assimilate nitrogen in biological systems by participating in the biosynthesis of amino acids, nucleic acids, and co-factors (Massire and Badet-Denisot, 1998)

[7] [8] It originated in northern Vanuatu, where it was domesticated by farmers around 3,000 years ago through selective cultivation