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In this paper, we systematically investigated the impact of copper and iron on the toxicity of various anticancer chelators
Sci ., 37 , 12251235
Another study demonstrated the typical characteristics of apoptosis in CEM T-leukemia human cells treated with CHE through the changes in the microstructure of EMC cells, which led to the further development of apoptosis, including fragmentation of DNA and reparation enzyme PARP-1 (Kaminskyy et al., 2008)
The NPs were well shielded against the early release of CDDP in the circulation since the PDA shell was stable at pH 7.4
