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Directly Observed Therapy Short Course (DOTS) DOTS is a case management strategy adopted in 1993 by the WHO to improve the effectiveness of compliance with treatment of TB and reduce the increasing global burden of the disease, especially in developing countries, but also in vulnerable population groups in developed countries

Future mechanism research directions Ongoing work expanding understanding and applications

It is well known that the hippocampal DG-CA3 system regulates structural plasticity, regenerative/remodeling capacity, as well as neurogenesis factors like brain-derived neurotrophic factor (Wang and Michaelis, 2010)

Based on the currently available research, GSH dosage, duration, and administration were consistent across all surveyed studies, with a daily oral dose of 300 mg [100,101,102]