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These may include: High-Performance Liquid Chromatography (HPLC) Mass Spectrometry (MS) Nuclear Magnetic Resonance (NMR) spectroscopy These methods can detect changes in the chemical composition of the product, including the formation of degradation products or impurities
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In most cases of vitamin B12 hypersensitivity, various types of allergic reactions to parenterally administered cobalamins (intramuscular or subcutaneous) have been described [9,10,11,12,13,82,83,84,85]
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