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lumbricoides cystatin regulates DC function through changes in the expression of mevalonate and cholesterol-related genes

doi: 10.1016/j.cbi.2008.07.009 111 SinghUDevarajSJialalI

Therefore, the key residues of Glu 115 and Asp 210 were responsible for the interaction of Rd and GPR30

Further, the study was also designed to test the homocysteine theory of depression, ie, circumventing the patients genetic inability to metabolize B vitamins by administering the metabolized forms in an optimal preparation for CNS availability would lower homocysteine, increase monoamine production, and facilitate clinical improvement