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doi: 10.1002/14651858.CD007910.pub2

80 So, while the results sound good, we have to view them as very low-quality evidence

These mechanisms lead to the prolonged activation of trigeminal neurons, astrocytes, and microglia around meningeal blood vessels, inflammatory cascades within brain parenchyma reaching the glia limitans, and the dispersal of arachidonic acid (AA) and potassium ions into the perivascular area (9, 10, 39)
