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Description
PT2385 is one of the very few HIF-2 inhibitors investigated in preclinical models of GBM and works by preventing allosteric heterodimerization with HIF-1 when it binds to HIF-2 PAS-B domain (156)
Furthermore, metabolic interaction between PSC and PDAC cells is a crucial factor in PDAC progression 14
The findings of this investigation imply that using SCSLNs may reduce Parkinsons disease symptoms via enhanced delivery of SC into the brain
Cancer Cell International
