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Malaguarnera, M., Risino, C., Cammalleri, L., Malaguarnera, L., Astuto, M., Vecchio, I., and Rampello, L

The Nrf2sMAF heterodimer binds to the antioxidant response element (ARE), which leads to the transcription of genes encoding antioxidant and detoxification enzymes such as SOD, CAT, GP X , heme oxygenase 1 (HO-1), NAD(P)H quinone dehydrogenase 1 (NQO1), which protect cells from oxidative stress and toxins (19, 124126) (Figure 3)

Serum Biomarkers of Muscle Damage and Antioxidant Status Subjects were fasted for 10 h prior to venous blood being extracted by venipuncture of the antecubital vein using a 21-gauge syringe and collected into an 8 mL collection tube containing serum separation gel (Vacuette , Refence # 155071P

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