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Mitochondrion is probably the most studied subcellular compartment due to its indispensable role in the regulation of cellular homeostasis and multifaceted functions
The key to NF-B activation is the phosphorylation of IB proteins, inhibitory proteins, on specific serines in the N -terminal, leading to ubiquitination and the subsequent proteasomal degradation (Figure 5)
Palmer BF (2002) Renal dysfunction complicating the treatment of hypertension
