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Hauck FH, Tanner SM, Henker J, Laass MW

Other established risk factors include: Hyperlipidemia Metabolic syndrome Obesity Atrial fibrillation Chronic kidney disease Sedentary lifestyle Sleep disorders, particularly obstructive sleep apnea Sleep disorders may contribute to CSVD through intermittent hypoxia, sympathetic activation, endothelial dysfunction, and impaired glymphatic clearance

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J Dent Res 88:461465 Anuradha CD, Kanno S, Hirano S (2001) Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL 60 cells