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Structure of parkin reveals mechanisms for ubiquitin ligase activation

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Because cancer cells do not take up aspartate very well, GOT fuels tumorigenesis by providing cytosolic aspartate, which is used as a precursor for protein and nucleotide synthesis and for redox homeostasis 32

J Sci Food Agric 98:22772284 Prosser RS, Anderson JC, Hanson ML, Solomon KR, Sibley PK (2016) Indirect effects of herbicides on biota in terrestrial edge-of-field habitats: a critical review of the literature