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& Engel, J

Previously, BPC 157 as an originally anti-ulcer peptide was implemented in inflammatory bowel disease trials [1015], and now multiple sclerosis [16], lethal dose (LD1) could be not achieved [1016]
The intestinal barrier is a selective barrierits function is to allow the transport of digested food essential for the bodys function, but at the same time to keep harmful substances and microorganisms in the intestinal lumen, which requires strict regulation of the barriers permeability [9, 19]

Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis
