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*Correspondence: Nicolas Rouhier, UMR1136, Interactions Arbres - Microorganismes, Facult des Sciences et Technologies, Universit de Lorraine, Boulevard des aiguillettes, F-54500 Vandoeuvre-ls-Nancy, France e-mail: [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology

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143 Heat shock proteins (HSPs) such as HSP70 and HSP90 also participate in the management of excess or deleterious proteins 144 and CHIP, an E3 ubiquitin ligase, can mediate the degradation of misfolded proteins associated with PD

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