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Such a system could help define functional subtypes based on pathogenic processes rather than surface phenotype alone

Alpha-tocopherol derivatives, such as acetate in alpha-tocopherol acetate, are cleaved prior to absorption in the small intestine by esterases, meaning that alpha-tocopherol is absorbed, not the alpha-tocopherol derivative

In response to these challenges, we recently developed and validated an anion-exchange chromatography coupled to high-resolution orbitrap MS (IC-MS) protocol, offering coverage of the central carbon metabolism and linear, reproducible loss of phosphates which does not alter the sample characteristics [31]

Wang, R., Yang, Z., Luo, J., Hsing, I