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We also provided preliminary evidence suggesting that, as in the BBDP rat model of the disease, zonulin up-regulation precedes the onset of diabetes in T1D patients (11)
Amelioration of endothelial dysfunction The vascular endothelium acts as a significant paracrine organ and is essential for controlling vascular tone, cell development, interactions between platelets and leukocytes, and the tendency to form clots [166, 167]
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