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FIGURE 3 2 Single components of natural products used for renal fibrosis Natural product constituents demonstrate notable efficacy in reversing or mitigating renal fibrosis through diverse molecular mechanisms

While modern cell membranes are primarily composed of phospholipids, such membranes are not appropriate for protocells due to their impermeability and slow molecular dynamics, which require protein transporters and flipases to allow internal metabolism and membrane growth

Therefore, positive coaggregation scores indicate decreased protein binary interaction while negative coaggregation scores indicate an increase in binary interactions

Walton FS, Harmon AW, Paul DS, Drobna Z, Patel YM, Styblo M: Inhibition of insulin-dependent glucose uptake by trivalent arsenicals: possible mechanism of arsenic-induced diabetes
