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PD is an incurable neurodegenerative disease and the levodopa ( L -DOPA) therapy can only alleviate PD symptoms, without any therapeutic improvements on the progression of DA neuronal degeneration [5]
Examining yet another mechanism, SF (0.03 to 3 M for 60 min) demonstrated six-fold greater potency against -site amyloid precursor protein cleaving enzyme 1 (BACE1), a rate-limiting enzyme in A production, as compared to resveratrol and quercetin in silico (71)
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Expression of the ACOT1, ACOT2, and ACOT4 genes is highest in adipose tissue, liver, heart, and kidney
