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aegypti it was previously observed high levels of glucose 6-phosphate dehydrogenase (G6PDH) activity at the very beginning of Aedes aegypti embryogenesis, which nevertheless decreased up to 5 HAE, indicating its significant involvement in the initial stages of embryonic development, prior to the retraction of the germ band (Vital et al., 2010)

Compared to cytosolic NADK (cNADK), mitochondrial NADK (mNADK) has a distinctive feature that it can directly phosphorylate nicotinamide adenine dinucleotide (NADH) to generate NADPH to alleviate oxidative stress in mitochondria

Hunt A, Harrington D, Robinson S

5 University of Pittsburgh, Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, Department of Emergency Medicine, Pittsburgh, United States Introduction: Sepsis is common, deadly, and heterogeneous