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At 99% steady-state, So, Taking the natural logarithm, Substitution for k = 0.693/ t 1/2 Accordingly, as a general example, if the t 1/2 for a drug is 6 hr, the time needed to reach 90%, 95%, and 99% of the steady-state is to be calculated

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Delker, C., Quint, M

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