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Clinical observations indicated that caution should be exercised when prescribing antidepressants, as misuse could lead to or worsen metabolic dysregulation (254, 255)
PMID: 62 JacobsJPGoudarziMSinghNTongMMcHardyIHRueggerPet al
The doses sound impressive, but without liposomal or other bioavailability-enhancing technology, a large fraction of that dose is degraded before it reaches systemic circulation
For example, accurate documentation of the dose of APAP ingested is extremely difficult, and APAP poisonings may be associated with ingestions of other medications
