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High-dose animal experiments and in-vitro studies have suggested potential effects of paracetamol on endocrine function, anandamide signaling, and oxidative stress (OS) (Sarzi-Puttini et al., 2024[94])

And there have been some randomized controlled clinical trials using nuts and seeds as well

Meakin, P

Furthermore, the acetyl moiety from ALCAR can enter the TCA cycle when metabolism via the pyruvate dehydrogenase complex is impaired as occurs in hypoxia and traumatic brain injury [103, 118122]
