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Research Applications: Investigated in tissue and cellular repair models Studied in peptide-mediated signaling pathways Explored in regenerative research environments Product Details: 5mg / 10mg per vial 99% purity Lyophilized powder For details on designation see our Research Use Only policy

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The investigators attributed BPC-157s pro-angiogenic effects to upregulation of vascular endothelial growth factor receptor 2 (VEGFR2), with downstream activation of the protein kinase B (Akt) and endothelial nitric oxide synthase (eNOS) pathway [1]

This dysfunction is caused by several factors, including vagal dysfunction, impaired activity of interstitial cells of Cajal (ICC), reduced neural nitric oxide synthase activity, and increased oxidative stress[101]