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doi: 10.3389/fncel.2025.1593963 Received 15 March 2025 Accepted 27 June 2025 Published 22 July 2025 Volume 19 - 2025 Edited by Alessandro Tozzi, University of Perugia, Italy Reviewed by Antonio Martnez-Ruiz, Princess University Hospital, Spain Mingzi Zhang, University of Southern California, United States Walter Moos, University of California, San Francisco, United States Updates Copyright 2025 Huang, Zhang, Chen, Wang and Zhou