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Description
DNA demethylation encompasses the removal of a methyl group (-CH3) from DNA and proceeds through two fundamental mechanisms: active demethylation, which implicates the TET enzyme family catalyzing the oxidation of the methyl group on cytosine, and passive demethylation, where DNA demethylase enzymes directly excise the methyl group from cytosine ( Figure 1 ) (3739)
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Association of common genetic variants in the MAP4K4 locus with prediabetic traits in humans
