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Ginsenoside Rg3 promotes the expression of multidrug resistance proteins (MRP) 1 and 3, activates Nrf2-mediated antioxidant gene expression, participates in detoxification, and reduces liver cytotoxicity (Gum and Cho, 2013a)

While large-scale clinical trials specifically for autoimmune indications remain limited, the existing research demonstrates a consistent pattern: thymosin alpha-1 supports immune regulation through multiple complementary pathways

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