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29,30 The oxygenation of C20-fatty acids from both 6 and 3 PUFAs produces a wide array of eicosanoid lipid mediators, including the well-studied prostaglandins (and their autoxidation analogues, the isoprostanes), thromboxanes, hydroxy-eicosatetraenoic acids (HETEs) and leukotrienes

Dihexa pairs particularly well with Semax and Selank (neurotransmitter modulation for real-time cognitive performance), NAD+ (mitochondrial support for neuronal energy), and SS-31 (mitochondrial membrane protection)

Journal of Neuroscience Research 16 (2): 367376

Sudden discontinuation can cause rebound acid hypersecretion, temporarily worsening symptoms