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The degenerative process of intervertebral discs is often accompanied by the overexpression of matrix metalloproteinases (MMP3, MMP13) and inflammatory factors (IL-1, IL-6, IL-8, PEG2, TNF-) (Wang et al., 2020)

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doi:10.1136/jcp.56.12.924 Hamaguchi Y, Kondoh T, Fukuda M, et al

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