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This targeted support for innate immunity is vital for patients whose natural defenses have been compromised by chronic illness

[DOI] [PMC free article] [PubMed] [Google Scholar] [83].Montero D, Walther G, Stehouwer CD, Houben AJ, Beckman JA, Vinet A, Effect of antioxidant vitamin supplementation on endothelial function in type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials

In the former, hormones interact with nuclear receptors, while in the latter, they may act independently of these receptors, directly affecting the cell membranes of cardiomyocytes and blood vessels [4]

In vitro experiments suggest that GSH is a poor substrate for Ero1 (Tu & Weissman, 2002)