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Evolving Therapeutics in Multiple Myeloma Highly effective treatments are available in early-line settings of multiple myeloma management, such as proteasome inhibitors, immunomodulatory drugs (IMiDs), corticosteroids, and multiple drug combinations, including anti-CD38 antibodies, but treatment options for progressive disease following initial lines of therapy have historically been limited

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It serves critical roles in cellular redox reactions for energy metabolism and acts as an essential substrate for key signaling enzymes regulating DNA repair, gene expression, and cell signaling

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