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The Biological Architect
Within the mitochondriathe energy-producing centers of cellsglutathione serves as a key regulator of redox homeostasis
In the treatment of breast cancer, anti-estrogen tamoxifen, the drug most often used for the long-term treatment of early breast cancer, can induce apoptosis in many cells, and this effect may be mediated by ROS generation in the mitochondria of breast cancer cells [71]
Adverse remodeling in an explanted human heart with IOC A 16-year-old girl with -thalassemia major was admitted with refractory heart failure (HF)
