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Stress increases energy demands in the brain, and though vital, energy production can be a messy job, creating a lot of free radicals.[1][2] Add to this inflammation from numerous sources, and something needs to be present to counterbalance it

These complex interactions of TNF- with numerous pathways imply that modulating this cytokine could yield synergistic protective benefits in ischemia-reperfusion injury 21

It is a copper binding tripeptide that modulates tissue repair pathways, extracellular matrix remodeling, and gene expression related to inflammation and regeneration
